High antibacterial activity and selectivity
Web10 de abr. de 2024 · Silver nanoparticles (AgNPs) are remarkably able to eliminate microorganisms, but induce cytotoxicity in mammalian cells, and zinc oxide … Web11 de jul. de 2024 · The obtained polypeptoid sulfoniums, with high selectivity and potent antibacterial property, are excellent candidates for antibacterial treatment and open up …
High antibacterial activity and selectivity
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Web1 de jan. de 2024 · From poly (vinylimidazole) to cationic glycopolymers and glyco-particles: effective antibacterial agents with enhanced biocompatibility and selectivity January 2024 Authors: Jing Chen Chunyang... Web9 de set. de 2024 · We showed that the antibacterial activity of specific lipopeptides depends on the peptide hydrophobicity and on the location of the hydrophobic amino …
Web26 de ago. de 2024 · Sulfonium-ion-containing polymers exhibit significant potential benefits for various applications. An efficient strategy to synthesize a type of antibacterial sulfonium-ion-bearing polypeptoids via a combination of ring-opening polymerization and a post-polymerization functionalization with various functional epoxides is presented. Web25 de set. de 2014 · Europe PMC is an archive of life sciences journal literature. On the basis of cell cultures involving bacterial strains (Escherichia coli 5α and Bacillus subtilis 168) and a mammalian cell line (NIH 3T3), the potent antibacterial activity and distinct selectivity from designed amphiphilic peptides G(IIKK)nI-NH2 (n = 2-4) have been …
Web26 de ago. de 2024 · A facile method to enhance the surface antibacterial activity by construction of an imidazolium-based polypeptide with fosfomycin counteranions (i.e., S4-PIL-FS) is reported, which displayed a synergistic antibacterial effect from the combination of membrane disruption and inhibition of initial cell wall synthesis, leading to higher in … WebThe obtained polypeptoid sulfoniums, with high selectivity and potent antibacterial property, are excellent candidates for antibacterial treatment and open up new possibilities for the preparation of a class of innovative antimicrobials.
Web12 de out. de 2015 · The antibacterial activity of PHLG-BIm was evaluated by the minimal inhibitory concentration (MIC) of the polypeptide against bacteria . With an RA structure, …
WebThe AAPEAs possessed high antibacterial and anti-biofilm activity, thus, they are promising to be used as long-term and biofilm-disrupting antimicrobial agents. … highland drake steel and yellowWebWith a relatively good therapeutic window corroborated by the observed selectivity of these compounds towards PE compared to phosphatidylcholine (PC) – the main phospholipid in mammalian membranes, the 4,6‐deoxygenation pattern of compound 7 was considered the key structural feature for maximized antibacterial activity of dodecyl deoxyglycosides … how is chris noth doingWebHelix-hinge-helix structure is a frequent feature for longer peptides with promising antibacterial selectivity, which can span the membrane. Sequence profile of … highland drake wowheadWeb8 de out. de 2014 · The high cellular selectivity, low toxicity toward mammalian hosts and noninducing bacterial resistance indicate great potential for developing the … how is chris evert doingWeb27 de ago. de 2014 · There was substantial selectivity in some orders. Proteales species had very high activity against the fungi but very low activity against the bacteria. The species in the Celastrales and Rosales had very low antifungal activity, low activity against Gram-negative bacteria and very high activity against Gram-positive bacteria. Conclusion highland drake stripes patternWeb11 de fev. de 2024 · Membrane-active amino acid-coupled polyetheramine derivatives with high selectivity and broad-spectrum antibacterial activity. Huan Li Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, Institute of Advanced Marine Materials, College of Materials Science and Chemical Engineering, Harbin … highland drake toothyWebBy high throughput screening, we identified a novel class of ... Importantly, some of the inhibitors showed antibacterial activity at low micromolar concentration ... They are … highland drake stripe pattern