WebDec 1, 2024 · Tezcan et al. [70] described a HPLC-PDA method for monitoring the plasma concentration of free cisplatin in different types of cancer. Deproteinization with cold MeOH was used for sample extraction of cisplatin and NiCI 2 .6.H 2 O as IS. Webneeded. As cisplatin is a metal-based molecule, historical analyses include phosphorescence, high-performance liquid chromatography with ultraviolet visible …
Effect of different shielding conditions on the stability of Cisplatin ...
WebMaterials and Methods Chemicals. Reduced glutathione (GSH), glutathione oxidized, and g-glutamyl glutamate, superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase, solvents of analytical grade (methanol and glacial acetic acid) used for HPLC, thioctic acid (a-lipoic acid, oxidized form) and cisplatin were purchased ... WebSep 1, 2016 · An isocratic reversed-phase high-performance liquid chromatographic method with ultraviolet detection at 254 nm has been developed for the determination of doxorubicin in human plasma. Plasma... posse konjugation präsens latein
Design of a Novel Theranostic Nanomedicine (III): Synthesis and ...
WebCisplatin is an antineoplastic drug used for the treatment of cancer patients with a variety of different malignancies. Application Cisplatin may be used as an analytical reference standard for the determination of the analyte in plasma, cancer cell, and tumor samples by high-performance liquid chromatographic assay. WebApr 24, 2024 · Doxorubicin hydrochloride. Several methods such as LC-MS, reverse phase HPLC and UV-Visible spectrometry have been reported and validated for quantitative analysis of doxorubicin hydrochloride in bulk and pharmaceutical dosage forms [12,13,14, 22, 23].All these methods require use of solvents, however due to unstable … WebJun 4, 2000 · The cisplatin recovered in the swabbing solution can be analyzed by HPLC using direct injection or preconcentration, depending on the expected level of cisplatin in the sample. Initial methods were developed to quantitate at a cisplatin concentration of about 100 PPB or higher in solution extracted from surfaces. posse jose sarney